6EWZ
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state
Summary for 6EWZ
Entry DOI | 10.2210/pdb6ewz/pdb |
Descriptor | GTP pyrophosphokinase, GUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total) |
Functional Keywords | magic spot, (p)ppgpp, small alarmone synthetase, persistence, resistance, mrsa, staphylococcus, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 2 |
Total formula weight | 58349.50 |
Authors | Manav, M.C.,Brodersen, D.E. (deposition date: 2017-11-07, release date: 2018-01-24, Last modification date: 2024-01-17) |
Primary citation | Manav, M.C.,Beljantseva, J.,Bojer, M.S.,Tenson, T.,Ingmer, H.,Hauryliuk, V.,Brodersen, D.E. Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP. J. Biol. Chem., 293:3254-3264, 2018 Cited by PubMed: 29326162DOI: 10.1074/jbc.RA117.001374 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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