6EWC

Crystal structure of non-phosphorylated form of RLS PHOSPHOPEPTIDE BOUND TO HLA-A2 in complex with LILRB1

Summary for 6EWC

Entry DOI	10.2210/pdb6ewc/pdb
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Reticulophagy regulator 2, ... (4 entities in total)
Functional Keywords	lilrb1, nonphosphopeptide, peptide-mhc complex, hla-a2, tumour antigen, crystallisation chaperone, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	133008.12
Authors	Mohammed, F.,Stones, D.H.,Willcox, B.E. (deposition date: 2017-11-03, release date: 2018-11-07, Last modification date: 2024-01-17)
Primary citation	Mohammed, F.,Stones, D.H.,Willcox, B.E. Application of the immunoregulatory receptor LILRB1 as a crystallisation chaperone for human class I MHC complexes. J. Immunol. Methods, 464:47-56, 2019 Cited by PubMed: 30365927 DOI: 10.1016/j.jim.2018.10.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation