Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6EUZ

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK37)

Summary for 6EUZ
Entry DOI10.2210/pdb6euz/pdb
Related5F1R 6EUT 6EUU
DescriptorListeriolysin positive regulatory factor A, ISOPROPYL ALCOHOL, SODIUM ION, ... (5 entities in total)
Functional Keywordstranscription regulator, dna binding, 2-pyridone, drug design, listeria monocytogenes, dna binding protein
Biological sourceListeria monocytogenes
Total number of polymer chains2
Total formula weight55508.73
Authors
Begum, A.,Hall, M.,Grundstrom, C.,Kulen, M.,Lindgren, M.,Johansson, J.,Almqvist, F.,Sauer, U.H.,Sauer-Eriksson, A.E. (deposition date: 2017-10-31, release date: 2018-05-02, Last modification date: 2024-01-17)
Primary citationKulen, M.,Lindgren, M.,Hansen, S.,Cairns, A.G.,Grundstrom, C.,Begum, A.,van der Lingen, I.,Brannstrom, K.,Hall, M.,Sauer, U.H.,Johansson, J.,Sauer-Eriksson, A.E.,Almqvist, F.
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61:4165-4175, 2018
Cited by
PubMed: 29667825
DOI: 10.1021/acs.jmedchem.8b00289
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon