6ER7

CHEMOTAXIS PROTEIN CHEY FROM Pyrococcus horikoshiI

6ER7 の概要

• エントリーDOI: 10.2210/pdb6er7/pdb
• 分子名称: 120aa long hypothetical chemotaxis protein (CheY) (1 entity in total)
• 機能のキーワード: signal transduction protein, signaling protein
• 由来する生物種: Pyrococcus horikoshii
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 39572.09

構造登録者

Paithankar, K.S.,Enderle, M.E.,Wirthensohn, D.,Grininger, M.,Oesterhelt, D. (登録日: 2017-10-17, 公開日: 2018-10-31, 最終更新日: 2024-01-17)

主引用文献

Paithankar, K.S.,Enderle, M.,Wirthensohn, D.C.,Miller, A.,Schlesner, M.,Pfeiffer, F.,Rittner, A.,Grininger, M.,Oesterhelt, D.
Structure of the archaeal chemotaxis protein CheY in a domain-swapped dimeric conformation.
Acta Crystallogr.,Sect.F, 75:576-585, 2019

PubMed Abstract: Archaea are motile by the rotation of the archaellum. The archaellum switches between clockwise and counterclockwise rotation, and movement along a chemical gradient is possible by modulation of the switching frequency. This modulation involves the response regulator CheY and the archaellum adaptor protein CheF. In this study, two new crystal forms and protein structures of CheY are reported. In both crystal forms, CheY is arranged in a domain-swapped conformation. CheF, the protein bridging the chemotaxis signal transduction system and the motility apparatus, was recombinantly expressed, purified and subjected to X-ray data collection.

PubMed: 31475924
DOI: 10.1107/S2053230X19010896

実験手法

X-RAY DIFFRACTION (2.62 Å)