6ER5

X-ray structure of Trypanothione Reductase from Leishmania infantum in complex with 2-(diethylamino)ethyl 4-((3-(4-nitrophenyl)-3-oxopropyl)amino)benzoate

6ER5 の概要

• エントリーDOI: 10.2210/pdb6er5/pdb
• 分子名称: Trypanothione reductase, FLAVIN-ADENINE DINUCLEOTIDE, 2-(diethylamino)ethyl 4-((3-(4-nitrophenyl)-3-oxopropyl)amino)benzoate, ... (4 entities in total)
• 機能のキーワード: trypanothione, trypanothione reductase, leishmania infantum trypanothione reductase inhibitors., oxidoreductase
• 由来する生物種: Leishmania infantum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54162.99

構造登録者

Ilari, A.,Fiorillo, A. (登録日: 2017-10-17, 公開日: 2018-10-31, 最終更新日: 2024-01-17)

• 主引用文献: Turcano, L.,Torrente, E.,Missineo, A.,Andreini, M.,Gramiccia, M.,Di Muccio, T.,Genovese, I.,Fiorillo, A.,Harper, S.,Bresciani, A.,Colotti, G.,Ilari, A.; Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening.; Plos Negl Trop Dis, 12:e0006969-e0006969, 2018; PubMed: 30475811; DOI: 10.1371/journal.pntd.0006969

実験手法

X-RAY DIFFRACTION (3.37 Å)