6EPH

Structure of the epsilon_1 / zeta_1 antitoxin toxin system from Neisseria gonorrhoeae in complex with UNAM.

Summary for 6EPH

• Entry DOI: 10.2210/pdb6eph/pdb
• Descriptor: Epsilon_1 antitoxin, Zeta_1 toxin, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, ... (6 entities in total)
• Functional Keywords: bacterial toxin antitoxin systems, small molecule kinases, toxin
• Biological source: Neisseria gonorrhoeae; More
• Total number of polymer chains: 8
• Total formula weight: 211952.14

Authors

Rocker, A.,Meinhart, A. (deposition date: 2017-10-11, release date: 2018-05-02, Last modification date: 2024-01-17)

• Primary citation: Rocker, A.,Peschke, M.,Kittila, T.,Sakson, R.,Brieke, C.,Meinhart, A.; The ng_ zeta 1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.; Nat Commun, 9:1686-1686, 2018; PubMed: 29703974; DOI: 10.1038/s41467-018-03652-8

Experimental method

X-RAY DIFFRACTION (2.7 Å)