6EPE

Substrate processing state 26S proteasome (SPS2)

Summary for 6EPE

Entry DOI	10.2210/pdb6epe/pdb
EMDB information	3915
Descriptor	Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (32 entities in total)
Functional Keywords	ups, substrate processing state, neuron degeneration, hydrolase
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	32
Total formula weight	1284003.13
Authors	Guo, Q.,Lehmer, C.,Martinez-Sanchez, A.,Rudack, T.,Beck, F.,Hartmann, H.,Hipp, M.S.,Hartl, F.U.,Edbauer, D.,Baumeister, W.,Fernandez-Busnadiego, R. (deposition date: 2017-10-11, release date: 2018-02-07, Last modification date: 2019-12-11)
Primary citation	Guo, Q.,Lehmer, C.,Martinez-Sanchez, A.,Rudack, T.,Beck, F.,Hartmann, H.,Perez-Berlanga, M.,Frottin, F.,Hipp, M.S.,Hartl, F.U.,Edbauer, D.,Baumeister, W.,Fernandez-Busnadiego, R. In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172:696-705.e12, 2018 Cited by PubMed: 29398115 DOI: 10.1016/j.cell.2017.12.030 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (12.8 Å)

Structure validation