6EPB
Structure of Chitinase 42 from Trichoderma harzianum
Summary for 6EPB
| Entry DOI | 10.2210/pdb6epb/pdb |
| Descriptor | Endochitinase 42, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
| Functional Keywords | hydrolase, carbohydrates, catalysis, catalytic domain, cloning, glycoside hydrolases, fungal proteins, transglycosilation, chitinase. |
| Biological source | Trichoderma harzianum (Hypocrea lixii) |
| Total number of polymer chains | 1 |
| Total formula weight | 48074.76 |
| Authors | Ramirez-Escudero, M.,Jimenez-Ortega, E.,Sanz-Aparicio, J. (deposition date: 2017-10-11, release date: 2018-09-26, Last modification date: 2024-01-17) |
| Primary citation | Kidibule, P.E.,Santos-Moriano, P.,Jimenez-Ortega, E.,Ramirez-Escudero, M.,Limon, M.C.,Remacha, M.,Plou, F.J.,Sanz-Aparicio, J.,Fernandez-Lobato, M. Use of chitin and chitosan to produce new chitooligosaccharides by chitinase Chit42: enzymatic activity and structural basis of protein specificity. Microb. Cell Fact., 17:47-47, 2018 Cited by PubMed Abstract: Chitinases are ubiquitous enzymes that have gained a recent biotechnological attention due to their ability to transform biological waste from chitin into valued chito-oligomers with wide agricultural, industrial or medical applications. The biological activity of these molecules is related to their size and acetylation degree. Chitinase Chit42 from Trichoderma harzianum hydrolyses chitin oligomers with a minimal of three N-acetyl-D-glucosamine (GlcNAc) units. Gene chit42 was previously characterized, and according to its sequence, the encoded protein included in the structural Glycoside Hydrolase family GH18. PubMed: 29566690DOI: 10.1186/s12934-018-0895-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report
