6EPB

Structure of Chitinase 42 from Trichoderma harzianum

6EPB の概要

• エントリーDOI: 10.2210/pdb6epb/pdb
• 分子名称: Endochitinase 42, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: hydrolase, carbohydrates, catalysis, catalytic domain, cloning, glycoside hydrolases, fungal proteins, transglycosilation, chitinase.
• 由来する生物種: Trichoderma harzianum (Hypocrea lixii)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48074.76

構造登録者

Ramirez-Escudero, M.,Jimenez-Ortega, E.,Sanz-Aparicio, J. (登録日: 2017-10-11, 公開日: 2018-09-26, 最終更新日: 2024-01-17)

主引用文献

Kidibule, P.E.,Santos-Moriano, P.,Jimenez-Ortega, E.,Ramirez-Escudero, M.,Limon, M.C.,Remacha, M.,Plou, F.J.,Sanz-Aparicio, J.,Fernandez-Lobato, M.
Use of chitin and chitosan to produce new chitooligosaccharides by chitinase Chit42: enzymatic activity and structural basis of protein specificity.
Microb. Cell Fact., 17:47-47, 2018

PubMed Abstract: Chitinases are ubiquitous enzymes that have gained a recent biotechnological attention due to their ability to transform biological waste from chitin into valued chito-oligomers with wide agricultural, industrial or medical applications. The biological activity of these molecules is related to their size and acetylation degree. Chitinase Chit42 from Trichoderma harzianum hydrolyses chitin oligomers with a minimal of three N-acetyl-D-glucosamine (GlcNAc) units. Gene chit42 was previously characterized, and according to its sequence, the encoded protein included in the structural Glycoside Hydrolase family GH18.

PubMed: 29566690
DOI: 10.1186/s12934-018-0895-x

実験手法

X-RAY DIFFRACTION (1.75 Å)