6ENB
LTA4 hydrolase (E297Q) mutant in complex with Pro-Gly-Pro peptide
Summary for 6ENB
Entry DOI | 10.2210/pdb6enb/pdb |
Descriptor | Leukotriene A-4 hydrolase, PRO-GLY-PRO, ZINC ION, ... (7 entities in total) |
Functional Keywords | lta4h, substrate, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 70097.76 |
Authors | Srinivas, H. (deposition date: 2017-10-04, release date: 2017-12-13, Last modification date: 2024-05-08) |
Primary citation | Numao, S.,Hasler, F.,Laguerre, C.,Srinivas, H.,Wack, N.,Jager, P.,Schmid, A.,Osmont, A.,Rothlisberger, P.,Houguenade, J.,Bergsdorf, C.,Dawson, J.,Carte, N.,Hofmann, A.,Markert, C.,Hardaker, L.,Billich, A.,Wolf, R.M.,Penno, C.A.,Bollbuck, B.,Miltz, W.,Rohn, T.A. Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors. Sci Rep, 7:13591-13591, 2017 Cited by PubMed: 29051536DOI: 10.1038/s41598-017-13490-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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