6EN1

Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6a-DNA)

6EN1 の概要

• エントリーDOI: 10.2210/pdb6en1/pdb
• 関連するPDBエントリー: 6EMY 6EMZ 6EN0
• 分子名称: Int protein, DNA (45-MER), DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• 機能のキーワード: transposase protein - dna complex, tyrosine recombinase, y-transposase, tn916-like conjugative transposon, antibiotic resistance transfer, recombination
• 由来する生物種: Enterococcus faecalis (Streptococcus faecalis); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 100423.51

構造登録者

Rubio-Cosials, A.,Barabas, O. (登録日: 2017-10-04, 公開日: 2018-04-04, 最終更新日: 2024-01-17)

• 主引用文献: Rubio-Cosials, A.,Schulz, E.C.,Lambertsen, L.,Smyshlyaev, G.,Rojas-Cordova, C.,Forslund, K.,Karaca, E.,Bebel, A.,Bork, P.,Barabas, O.; Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.; Cell, 173:208-220.e20, 2018; PubMed: 29551265; DOI: 10.1016/j.cell.2018.02.032

実験手法

X-RAY DIFFRACTION (2.67 Å)