6EK2
CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH SINGLE CHAIN FV FRAGMENT 10
Summary for 6EK2
Entry DOI | 10.2210/pdb6ek2/pdb |
Related | 5DFW 6EJG 6EJM |
Descriptor | CD81 antigen, SINGLE CHAIN FV FRAGMENT (3 entities in total) |
Functional Keywords | helical bundle, antibody-antigen complex, cell adhesion |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 74350.33 |
Authors | Harris, S.F.,Villasenor, A.,Kuglstatter, A. (deposition date: 2017-09-25, release date: 2018-05-30, Last modification date: 2018-06-20) |
Primary citation | Nelson, B.,Adams, J.,Kuglstatter, A.,Li, Z.,Harris, S.F.,Liu, Y.,Bohini, S.,Ma, H.,Klumpp, K.,Gao, J.,Sidhu, S.S. Structure-Guided Combinatorial Engineering Facilitates Affinity and Specificity Optimization of Anti-CD81 Antibodies. J. Mol. Biol., 430:2139-2152, 2018 Cited by PubMed: 29778602DOI: 10.1016/j.jmb.2018.05.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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