6ECL

Crystal Structure of a 1,2,4-Triazole Allosteric RNase H Inhibitor in Complex with HIV Reverse Transcriptase

6ECL の概要

• エントリーDOI: 10.2210/pdb6ecl/pdb
• 分子名称: Reverse transcriptase/ribonuclease H, MANGANESE (II) ION, 1-[4-methoxy-3-[[5-methyl-4-(phenylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]ethanone, ... (5 entities in total)
• 機能のキーワード: hiv-1, reverse transcriptase, rnase h, inhibitor, transferase
• 由来する生物種: Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114679.32

構造登録者

Kirby, K.A.,Sarafianos, S.G. (登録日: 2018-08-08, 公開日: 2019-08-21, 最終更新日: 2023-10-11)

• 主引用文献: Kirby, K.A.,Sarafianos, S.G.; Crystal Structure of a 1,2,4-Triazole Allosteric RNase H Inhibitor in Complex with HIV Reverse Transcriptase; To be published,

実験手法

X-RAY DIFFRACTION (2.385 Å)