6E8U
Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin
Summary for 6E8U
Entry DOI | 10.2210/pdb6e8u/pdb |
Descriptor | RNA (37-MER), MAGNESIUM ION, 4-[(3-{2,16-dioxo-20-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, ... (6 entities in total) |
Functional Keywords | aptamer, fluorescence, rna, g-quadruplex |
Biological source | synthetic construct |
Total number of polymer chains | 1 |
Total formula weight | 13007.72 |
Authors | Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2018-07-31, release date: 2019-04-17, Last modification date: 2023-10-11) |
Primary citation | Trachman 3rd., R.J.,Autour, A.,Jeng, S.C.Y.,Abdolahzadeh, A.,Andreoni, A.,Cojocaru, R.,Garipov, R.,Dolgosheina, E.V.,Knutson, J.R.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R. Structure and functional reselection of the Mango-III fluorogenic RNA aptamer. Nat. Chem. Biol., 15:472-479, 2019 Cited by PubMed: 30992561DOI: 10.1038/s41589-019-0267-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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