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6E8U

Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin

Summary for 6E8U
Entry DOI10.2210/pdb6e8u/pdb
DescriptorRNA (37-MER), MAGNESIUM ION, 4-[(3-{2,16-dioxo-20-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, ... (6 entities in total)
Functional Keywordsaptamer, fluorescence, rna, g-quadruplex
Biological sourcesynthetic construct
Total number of polymer chains1
Total formula weight13007.72
Authors
Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2018-07-31, release date: 2019-04-17, Last modification date: 2023-10-11)
Primary citationTrachman 3rd., R.J.,Autour, A.,Jeng, S.C.Y.,Abdolahzadeh, A.,Andreoni, A.,Cojocaru, R.,Garipov, R.,Dolgosheina, E.V.,Knutson, J.R.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R.
Structure and functional reselection of the Mango-III fluorogenic RNA aptamer.
Nat. Chem. Biol., 15:472-479, 2019
Cited by
PubMed: 30992561
DOI: 10.1038/s41589-019-0267-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

217705

數據於2024-03-27公開中

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