6E8U

Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin

6E8U の概要

• エントリーDOI: 10.2210/pdb6e8u/pdb
• 分子名称: RNA (37-MER), MAGNESIUM ION, 4-[(3-{2,16-dioxo-20-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, ... (6 entities in total)
• 機能のキーワード: aptamer, fluorescence, rna, g-quadruplex
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13007.72

構造登録者

Trachman, R.J.,Ferre-D'Amare, A.R. (登録日: 2018-07-31, 公開日: 2019-04-17, 最終更新日: 2023-10-11)

• 主引用文献: Trachman 3rd., R.J.,Autour, A.,Jeng, S.C.Y.,Abdolahzadeh, A.,Andreoni, A.,Cojocaru, R.,Garipov, R.,Dolgosheina, E.V.,Knutson, J.R.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R.; Structure and functional reselection of the Mango-III fluorogenic RNA aptamer.; Nat. Chem. Biol., 15:472-479, 2019; PubMed: 30992561; DOI: 10.1038/s41589-019-0267-9

実験手法

X-RAY DIFFRACTION (1.55 Å)