6E8C

Crystal structure of the double homeodomain of DUX4 in complex with DNA

Summary for 6E8C

• Entry DOI: 10.2210/pdb6e8c/pdb
• Descriptor: Double homeobox protein 4, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... (4 entities in total)
• Functional Keywords: transcription factor, double homeodomain, transcription-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 27032.74

Authors

Lee, J.K.,Bosnakovski, D.,Toso, E.A.,Dinh, T.,Banerjee, S.,Bohl, T.E.,Shi, K.,Kurahashi, K.,Kyba, M.,Aihara, H. (deposition date: 2018-07-27, release date: 2018-12-26, Last modification date: 2023-10-11)

• Primary citation: Lee, J.K.,Bosnakovski, D.,Toso, E.A.,Dinh, T.,Banerjee, S.,Bohl, T.E.,Shi, K.,Orellana, K.,Kyba, M.,Aihara, H.; Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.; Cell Rep, 25:2955-2962.e3, 2018; PubMed: 30540931; DOI: 10.1016/j.celrep.2018.11.060

Experimental method

X-RAY DIFFRACTION (2.12 Å)