6E85

1.25 Angstrom Resolution Crystal Structure of 4-hydroxythreonine-4-phosphate Dehydrogenase from Klebsiella pneumoniae.

6E85 の概要

• エントリーDOI: 10.2210/pdb6e85/pdb
• 分子名称: D-threonate 4-phosphate dehydrogenase, NICKEL (II) ION, FORMIC ACID, ... (7 entities in total)
• 機能のキーワード: structural genomics, center for structural genomics of infectious diseases, csgid, 4-hydroxythreonine-4-phosphate dehydrogenase, hydrolase
• 由来する生物種: Klebsiella pneumoniae subsp. pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71652.66

構造登録者

Minasov, G.,Shuvalova, L.,Dubrovska, I.,Kiryukhina, O.,Endres, M.,Satchell, K.J.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2018-07-27, 公開日: 2018-08-08, 最終更新日: 2023-10-25)

主引用文献

Inniss, N.L.,Kochan, T.J.,Minasov, G.,Wawrzak, Z.,Chang, C.,Tan, K.,Shuvalova, L.,Kiryukhina, O.,Pshenychnyi, S.,Wu, R.,Dubrovska, I.,Babnigg, G.,Endres, M.,Anderson, W.F.,Hauser, A.R.,Joachimiak, A.,Satchell, K.J.F.
A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12:e0101322-e0101322, 2023

PubMed Abstract: Klebsiella pneumoniae is a leading cause of antibiotic-resistant-associated deaths in the world. Here, we report the deposition of 14 structures of enzymes from both the core and accessory genomes of sequence type 23 (ST23) K1 hypervirulent K. pneumoniae.

PubMed: 36695589
DOI: 10.1128/mra.01013-22

実験手法

X-RAY DIFFRACTION (1.25 Å)