6E7R

Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-4

6E7R の概要

• エントリーDOI: 10.2210/pdb6e7r/pdb
• 分子名称: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2B, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: nmda receptor, ion channel, allosteric modulation, extracellular domain, transport protein
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 172886.77

構造登録者

Regan, M.C.,Furukawa, H. (登録日: 2018-07-27, 公開日: 2019-01-30, 最終更新日: 2023-10-11)

• 主引用文献: Regan, M.C.,Zhu, Z.,Yuan, H.,Myers, S.J.,Menaldino, D.S.,Tahirovic, Y.A.,Liotta, D.C.,Traynelis, S.F.,Furukawa, H.; Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors; Nat Commun, 10:321-, 2019

実験手法

X-RAY DIFFRACTION (2.1 Å)