6E4X

Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)

Summary for 6E4X

DescriptorHemagglutinin, S5V2-29 light chain, S5V2-29 heavy chain, ... (9 entities in total)
Functional Keywordsinfluenza antibody, viral protein-immune system complex, viral protein/immune system
Biological sourceInfluenza A virus (A/Texas/50/2012(H3N2))
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Total number of polymer chains3
Total molecular weight84372.07
Authors
McCarthy, K.R.,Harrison, S.C. (deposition date: 2018-07-18, release date: 2019-05-22, Last modification date: 2019-05-29)
Primary citation
Watanabe, A.,McCarthy, K.R.,Kuraoka, M.,Schmidt, A.G.,Adachi, Y.,Onodera, T.,Tonouchi, K.,Caradonna, T.M.,Bajic, G.,Song, S.,McGee, C.E.,Sempowski, G.D.,Feng, F.,Urick, P.,Kepler, T.B.,Takahashi, Y.,Harrison, S.C.,Kelsoe, G.
Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177:1124-1135.e16, 2019
PubMed: 31100267 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2019.03.048
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2246 0.1% 2.2% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution