6E42

CRYSTAL STRUCTURE OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) in complex with ferric heme and 4-Chlorophenyl imidazole

6E42 の概要

• エントリーDOI: 10.2210/pdb6e42/pdb
• 分子名称: Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-(3-chlorophenyl)-1H-imidazole, ... (5 entities in total)
• 機能のキーワード: ido1, 4-chlorophenyl imidazole, inhibitor complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 186622.40

構造登録者

Luo, S.,Tong, L. (登録日: 2018-07-16, 公開日: 2018-11-14, 最終更新日: 2024-03-13)

• 主引用文献: Luo, S.,Xu, K.,Xiang, S.,Chen, J.,Chen, C.,Guo, C.,Tong, Y.,Tong, L.; High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form.; Acta Crystallogr F Struct Biol Commun, 74:717-724, 2018; PubMed: 30387777; DOI: 10.1107/S2053230X18012955

実験手法

X-RAY DIFFRACTION (2.103 Å)