6E31
Crystal structure of RIAM in an autoinhibited configuration.
Summary for 6E31
| Entry DOI | 10.2210/pdb6e31/pdb |
| Descriptor | Rap1-interacting adapter molecule (2 entities in total) |
| Functional Keywords | riam, rap1, lpd, adhesion, ras-association domain, pleckstrin-homology domain, autoinhibition, cell adhesion |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 41883.56 |
| Authors | Chang, Y.C.,Su, W.,Zhang, H.,Huang, Q.,Philips, M.R.,Wu, J. (deposition date: 2018-07-12, release date: 2019-02-20, Last modification date: 2023-10-11) |
| Primary citation | Chang, Y.C.,Su, W.,Cho, E.A.,Zhang, H.,Huang, Q.,Philips, M.R.,Wu, J. Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation. Proc. Natl. Acad. Sci. U.S.A., 116:3524-3529, 2019 Cited by PubMed: 30733287DOI: 10.1073/pnas.1818880116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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