6E2J
Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B
Summary for 6E2J
Entry DOI | 10.2210/pdb6e2j/pdb |
Descriptor | Keratin, type II cytoskeletal 1, Keratin, type I cytoskeletal 10, SULFATE ION, ... (4 entities in total) |
Functional Keywords | intermediate filament, keratin, coiled-coil, skin, protein fibril |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 25296.06 |
Authors | Eldirany, S.A.,Lomakin, I.B.,Bunick, C.G. (deposition date: 2018-07-11, release date: 2019-05-15, Last modification date: 2024-03-13) |
Primary citation | Eldirany, S.A.,Ho, M.,Hinbest, A.J.,Lomakin, I.B.,Bunick, C.G. Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly. Embo J., 38:-, 2019 Cited by PubMed: 31036554DOI: 10.15252/embj.2018100741 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.386 Å) |
Structure validation
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