6E2J

Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B

6E2J の概要

• エントリーDOI: 10.2210/pdb6e2j/pdb
• 分子名称: Keratin, type II cytoskeletal 1, Keratin, type I cytoskeletal 10, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: intermediate filament, keratin, coiled-coil, skin, protein fibril
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25296.06

構造登録者

Eldirany, S.A.,Lomakin, I.B.,Bunick, C.G. (登録日: 2018-07-11, 公開日: 2019-05-15, 最終更新日: 2024-03-13)

• 主引用文献: Eldirany, S.A.,Ho, M.,Hinbest, A.J.,Lomakin, I.B.,Bunick, C.G.; Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.; Embo J., 38:-, 2019; PubMed: 31036554; DOI: 10.15252/embj.2018100741

実験手法

X-RAY DIFFRACTION (2.386 Å)