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6E1F

Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1

Summary for 6E1F
Entry DOI10.2210/pdb6e1f/pdb
DescriptorLysine-specific histone demethylase 1A, SULFATE ION (3 entities in total)
Functional Keywordshistone lysine specific demethylase, swirm domain, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight41126.51
Authors
Luka, Z.,Pakhomova, S.,Reiter, N.J. (deposition date: 2018-07-09, release date: 2019-07-10, Last modification date: 2023-10-11)
Primary citationZeng, D.,Brown, B.P.,Luka, Z.,Pakhomova, S.,Martin, B.,Moore, K.,Meiler, J.,Reiter, N.J.
Transient and highly ordered structural domains exist within the N-terminus of LSD1 and differentially interact with mononucleosomes
To be Published,
Experimental method
X-RAY DIFFRACTION (1.16 Å)
Structure validation

218500

數據於2024-04-17公開中

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