6E1F

Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1

6E1F の概要

分子名称Lysine-specific histone demethylase 1A, SULFATE ION (3 entities in total)
機能のキーワードhistone lysine specific demethylase, swirm domain, oxidoreductase
由来する生物種Homo sapiens (Human)
ポリマー鎖数4
分子量合計41126.51
構造登録者
Luka, Z.,Pakhomova, S.,Reiter, N.J. (登録日: 2018-07-09, 公開日: 2019-07-10)
主引用文献
Zeng, D.,Brown, B.P.,Luka, Z.,Pakhomova, S.,Martin, B.,Moore, K.,Meiler, J.,Reiter, N.J.
Transient and highly ordered structural domains exist within the N-terminus of LSD1 and differentially interact with mononucleosomes
To be Published,
実験手法
X-RAY DIFFRACTION (1.16 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16960 1.3% 7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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