6E0P

Cryo-EM structure of the centromeric nucleosome (Native alpha satellite DNA) in complex with a single chain antibody fragment

Summary for 6E0P

• Entry DOI: 10.2210/pdb6e0p/pdb
• EMDB information: 8938 8945 8949
• Descriptor: Histone H3-like centromeric protein A, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
• Functional Keywords: cenp-a, centromere, native alpha satellite dna, anti-nucleosome antibody, acidic patch, nucleosome, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 262616.69

Authors

Yadav, K.N.S.,Zhou, B.-R. (deposition date: 2018-07-06, release date: 2019-05-22, Last modification date: 2019-12-18)

• Primary citation: Zhou, B.R.,Yadav, K.N.S.,Borgnia, M.,Hong, J.,Cao, B.,Olins, A.L.,Olins, D.E.,Bai, Y.,Zhang, P.; Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.; Nat Commun, 10:2301-2301, 2019; PubMed: 31127102; DOI: 10.1038/s41467-019-10247-4

Experimental method

ELECTRON MICROSCOPY (2.6 Å)