6E0N

Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with GTP and Apcpp

Summary for 6E0N

Entry DOI	10.2210/pdb6e0n/pdb
Descriptor	cGAS/DncV-like nucleotidyltransferase in E. coli homolog, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	cgas, dncv, cyclic dinucleotide, nucleotide second messenger, nucleotidyltransferase, transferase
Biological source	Elizabethkingia meningoseptica ATCC 13253 = NBRC 12535
Total number of polymer chains	1
Total formula weight	35775.15
Authors	Eaglesham, J.B.,Whiteley, A.T.,de Oliveira Mann, C.C.,Morehouse, B.R.,Nieminen, E.A.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J. (deposition date: 2018-07-06, release date: 2019-02-20, Last modification date: 2024-03-13)
Primary citation	Whiteley, A.T.,Eaglesham, J.B.,de Oliveira Mann, C.C.,Morehouse, B.R.,Lowey, B.,Nieminen, E.A.,Danilchanka, O.,King, D.S.,Lee, A.S.Y.,Mekalanos, J.J.,Kranzusch, P.J. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567:194-199, 2019 Cited by PubMed: 30787435 DOI: 10.1038/s41586-019-0953-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation