6E07

Crystal structure of Canton G6PD in complex with structural NADP

Replaces:  5VG5

Summary for 6E07

• Entry DOI: 10.2210/pdb6e07/pdb
• Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: g6pd, nadp, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 483686.11

Authors

Rahighi, S.,Mochly-Rosen, D.,Wakatsuki, S. (deposition date: 2018-07-06, release date: 2018-07-25, Last modification date: 2023-10-11)

• Primary citation: Hwang, S.,Mruk, K.,Rahighi, S.,Raub, A.G.,Chen, C.H.,Dorn, L.E.,Horikoshi, N.,Wakatsuki, S.,Chen, J.K.,Mochly-Rosen, D.; Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator.; Nat Commun, 9:4045-4045, 2018; PubMed: 30279493; DOI: 10.1038/s41467-018-06447-z

Experimental method

X-RAY DIFFRACTION (2.6 Å)