6DZM

Bundibugyo virus GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab

Summary for 6DZM

• Entry DOI: 10.2210/pdb6dzm/pdb
• EMDB information: 8936
• Descriptor: Bundibugyo virus GP1, Bundibugyo virus GP2, Antibody ADI-15878 Fab, light chain, ... (7 entities in total)
• Functional Keywords: antibody, pan-ebolavirus, internal fusion loop, hr1, glycoprotein, viral protein
• Biological source: Bundibugyo ebolavirus; More
• Total number of polymer chains: 12
• Total formula weight: 241609.54

Authors

Murin, C.D.,Ward, A.B. (deposition date: 2018-07-05, release date: 2018-09-12, Last modification date: 2020-07-29)

• Primary citation: Murin, C.D.,Bruhn, J.F.,Bornholdt, Z.A.,Copps, J.,Stanfield, R.,Ward, A.B.; Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop.; Cell Rep, 24:2723-2732.e4, 2018; PubMed: 30184505; DOI: 10.1016/j.celrep.2018.08.009

Experimental method

ELECTRON MICROSCOPY (4.29 Å)