6DVL
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-115
Summary for 6DVL
| Entry DOI | 10.2210/pdb6dvl/pdb |
| Descriptor | Hdac6 protein, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
| Functional Keywords | histone deacetylaase, metallohydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Danio rerio (Zebrafish) |
| Total number of polymer chains | 2 |
| Total formula weight | 81733.24 |
| Authors | Porter, N.J.,Christianson, D.W. (deposition date: 2018-06-24, release date: 2018-08-29, Last modification date: 2023-10-11) |
| Primary citation | Porter, N.J.,Osko, J.D.,Diedrich, D.,Kurz, T.,Hooker, J.M.,Hansen, F.K.,Christianson, D.W. Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity. J. Med. Chem., 61:8054-8060, 2018 Cited by PubMed: 30118224DOI: 10.1021/acs.jmedchem.8b01013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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