6DV5

Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution

Summary for 6DV5

• Entry DOI: 10.2210/pdb6dv5/pdb
• Descriptor: Heat shock protein beta-1 (1 entity in total)
• Functional Keywords: molecular chaperone, small heat shock protein, alpha crystallin domain, chaperone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 24
• Total formula weight: 547451.66

Authors

Aguda, A.H.,Brayer, G.D. (deposition date: 2018-06-22, release date: 2019-06-26, Last modification date: 2023-10-11)

• Primary citation: Nappi, L.,Aguda, A.H.,Al Nakouzi, N.,Lelj Garolla, B.,Beraldi, E.,Lallous, N.,Thi, M.,Moore, S.,Battsogt, D.,Stoffeliene, S.,Ban, F.,Nguyen, N.T.,Saxena, N.,Dueva, E.,Yamazaki, T.,Zoubeidi, A.,Cherkasov, A.,Brayer, G.D.,Gleave, M.; Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization.; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.58 Å)