6DV5

Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution

6DV5 の概要

• エントリーDOI: 10.2210/pdb6dv5/pdb
• 分子名称: Heat shock protein beta-1 (1 entity in total)
• 機能のキーワード: molecular chaperone, small heat shock protein, alpha crystallin domain, chaperone
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 24
• 化学式量合計: 547451.66

構造登録者

Aguda, A.H.,Brayer, G.D. (登録日: 2018-06-22, 公開日: 2019-06-26, 最終更新日: 2023-10-11)

• 主引用文献: Nappi, L.,Aguda, A.H.,Al Nakouzi, N.,Lelj Garolla, B.,Beraldi, E.,Lallous, N.,Thi, M.,Moore, S.,Battsogt, D.,Stoffeliene, S.,Ban, F.,Nguyen, N.T.,Saxena, N.,Dueva, E.,Yamazaki, T.,Zoubeidi, A.,Cherkasov, A.,Brayer, G.D.,Gleave, M.; Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization.; To Be Published,

実験手法

X-RAY DIFFRACTION (3.58 Å)