6DU5

Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6

6DU5 の概要

• エントリーDOI: 10.2210/pdb6du5/pdb
• 分子名称: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER) (2 entities in total)
• 機能のキーワード: m6a methylation, methyltransferase, protein-rna structure, m6a, n6-methyladenosine, transferase-rna complex, transferase/rna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44912.81

構造登録者

Doxtader, K.,Wang, P.,Nam, Y. (登録日: 2018-06-19, 公開日: 2018-09-26, 最終更新日: 2018-10-03)

• 主引用文献: Doxtader, K.A.,Wang, P.,Scarborough, A.M.,Seo, D.,Conrad, N.K.,Nam, Y.; Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.; Mol. Cell, 71:1001-1011.e4, 2018; PubMed: 30197297; DOI: 10.1016/j.molcel.2018.07.025

実験手法

X-RAY DIFFRACTION (3.006 Å)