6DRW
JAK2 JH1 in complex with JNJ-7706621 (Crystal Form 2)
Summary for 6DRW
Entry DOI | 10.2210/pdb6drw/pdb |
Descriptor | Tyrosine-protein kinase JAK2, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide (3 entities in total) |
Functional Keywords | kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 37792.76 |
Authors | Puleo, D.E.,Schlessinger, J. (deposition date: 2018-06-13, release date: 2018-07-18, Last modification date: 2024-10-23) |
Primary citation | Puleo, D.E.,Schlessinger, J. JAK2 JH2 Binders To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.303 Å) |
Structure validation
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