6DRJ

Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state

Summary for 6DRJ

Entry DOI	10.2210/pdb6drj/pdb
EMDB information	7999 8901
Descriptor	Transient receptor potential cation channel, subfamily M, member 2, ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION (3 entities in total)
Functional Keywords	transport protein
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	4
Total formula weight	675931.45
Authors	Du, J.,Lu, W.,Huang, Y.,Winkler, P.,Sun, W. (deposition date: 2018-06-12, release date: 2018-09-19, Last modification date: 2018-10-10)
Primary citation	Huang, Y.,Winkler, P.A.,Sun, W.,Lu, W.,Du, J. Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562:145-149, 2018 Cited by PubMed: 30250252 DOI: 10.1038/s41586-018-0558-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation