6DO2

Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine

6DO2 の概要

分子名称Endoplasmic reticulum chaperone BiP, 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (3 entities in total)
機能のキーワードhuman grp78, adenosine analog, chaperone, hydrolase
由来する生物種Homo sapiens (Human)
ポリマー鎖数2
分子量合計84871.99
構造登録者
Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W. (登録日: 2018-06-08, 公開日: 2019-06-12)
主引用文献
Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W.
Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine
To Be Published,
実験手法
X-RAY DIFFRACTION (1.7 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23820 0.8% 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード