6DJP
Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68
Summary for 6DJP
Entry DOI | 10.2210/pdb6djp/pdb |
EMDB information | 7939 |
Descriptor | Integrin alpha-v, 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-8, ... (10 entities in total) |
Functional Keywords | glycoprotein, membrane protein, adhesion, fab |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 274901.35 |
Authors | Cormier, A.,Campbell, M.G.,Nishimura, S.L.,Cheng, Y. (deposition date: 2018-05-25, release date: 2018-07-25, Last modification date: 2024-10-09) |
Primary citation | Cormier, A.,Campbell, M.G.,Ito, S.,Wu, S.,Lou, J.,Marks, J.,Baron, J.L.,Nishimura, S.L.,Cheng, Y. Cryo-EM structure of the alpha v beta 8 integrin reveals a mechanism for stabilizing integrin extension. Nat. Struct. Mol. Biol., 25:698-704, 2018 Cited by PubMed: 30061598DOI: 10.1038/s41594-018-0093-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.8 Å) |
Structure validation
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