6DJ3

Crystal structure of CNNM2 cyclic nucleotide-binding homology domain

Summary for 6DJ3

• Entry DOI: 10.2210/pdb6dj3/pdb
• Related: 6DFD
• Descriptor: Metal transporter CNNM2, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: cnnm2, cyclic nucleotide-binding homology domain, mg2+ transporter, transport protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 45640.37

Authors

Chen, Y.S.,Gehring, K. (deposition date: 2018-05-24, release date: 2018-10-31, Last modification date: 2023-10-11)

• Primary citation: Chen, Y.S.,Kozlov, G.,Fakih, R.,Funato, Y.,Miki, H.,Gehring, K.; The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.; J. Biol. Chem., 293:19998-20007, 2018; PubMed: 30341174; DOI: 10.1074/jbc.RA118.005672

Experimental method

X-RAY DIFFRACTION (2.6 Å)