6DHL

Bovine glutamate dehydrogenase complexed with epicatechin-3-gallate (ECG)

Replaces:  3QMUReplaces:  3MVQ

Summary for 6DHL

• Entry DOI: 10.2210/pdb6dhl/pdb
• Descriptor: Glutamate dehydrogenase 1, mitochondrial, (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate (2 entities in total)
• Functional Keywords: ecg, glutamate, dehydrogenase, inhibition, oxidoreductase
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 12
• Total formula weight: 666840.24

Authors

Smith, T.J. (deposition date: 2018-05-20, release date: 2018-07-25)

• Primary citation: Li, C.,Li, M.,Chen, P.,Narayan, S.,Matschinsky, F.M.,Bennett, M.J.,Stanley, C.A.,Smith, T.J.; Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site.; J. Biol. Chem., 286:34164-34174, 2011; PubMed: 21813650; DOI: 10.1074/jbc.M111.268599

Experimental method

X-RAY DIFFRACTION (3.624 Å)