6DGK

Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus

6DGK の概要

• エントリーDOI: 10.2210/pdb6dgk/pdb
• 分子名称: Non-structural protein 1 (2 entities in total)
• 機能のキーワード: influenza, ns1, effector domain, w187a, viral protein
• 由来する生物種: Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26973.13

構造登録者

Kleinpeter, A.B.,Green, T.J.,Petit, C.M. (登録日: 2018-05-17, 公開日: 2018-08-15, 最終更新日: 2024-03-13)

• 主引用文献: Kleinpeter, A.B.,Jureka, A.S.,Falahat, S.M.,Green, T.J.,Petit, C.M.; Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.; J. Biol. Chem., 293:14659-14668, 2018; PubMed: 30076219; DOI: 10.1074/jbc.RA118.004012

実験手法

X-RAY DIFFRACTION (1.9 Å)