6DFM
Crystal structure of human GRP78 in complex with 8-aminoadenosine
Summary for 6DFM
Entry DOI | 10.2210/pdb6dfm/pdb |
Descriptor | Endoplasmic reticulum chaperone BiP, (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol (3 entities in total) |
Functional Keywords | endoplasmic reticulum, unfolded protein response, nucleoside analog, chaperone |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 84875.94 |
Authors | Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W. (deposition date: 2018-05-15, release date: 2019-05-15, Last modification date: 2024-03-13) |
Primary citation | Ferrie, R.P.,Chen, Y.,Antoshchenko, T.,Cooney, O.M.,Huang, Y.,Park, H.W. Crystal structure of human GRP78 in complex with 8-aminoadenosine To be Published, |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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