6DFG

BG505 MD39 SOSIP trimer in complex with mature BG18 fragment antigen binding

Summary for 6DFG

• Entry DOI: 10.2210/pdb6dfg/pdb
• Related: 6DFH
• EMDB information: 7875 7876
• Descriptor: Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: hiv-1, hiv envelope, sosip, germline targeting, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 384555.97

Authors

Ozorowski, G.,Steichen, J.M.,Schief, W.R.,Ward, A.B. (deposition date: 2018-05-14, release date: 2019-11-06, Last modification date: 2020-07-29)

• Primary citation: Steichen, J.M.,Lin, Y.C.,Havenar-Daughton, C.,Pecetta, S.,Ozorowski, G.,Willis, J.R.,Toy, L.,Sok, D.,Liguori, A.,Kratochvil, S.,Torres, J.L.,Kalyuzhniy, O.,Melzi, E.,Kulp, D.W.,Raemisch, S.,Hu, X.,Bernard, S.M.,Georgeson, E.,Phelps, N.,Adachi, Y.,Kubitz, M.,Landais, E.,Umotoy, J.,Robinson, A.,Briney, B.,Wilson, I.A.,Burton, D.R.,Ward, A.B.,Crotty, S.,Batista, F.D.,Schief, W.R.; A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.; Science, 366:-, 2019; PubMed: 31672916; DOI: 10.1126/science.aax4380

Experimental method

ELECTRON MICROSCOPY (4.42 Å)