6DF9

Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)

6DF9 の概要

関連するPDBエントリー6DF5 6DF8
分子名称Transcriptional regulator Kaiso, DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), ... (6 entities in total)
機能のキーワードdna methylation, zinc finger, transcriptional regulator, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
由来する生物種Homo sapiens (Human)
詳細
ポリマー鎖数3
分子量合計27480.64
構造登録者
Nikolova, E.N.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E. (登録日: 2018-05-14, 公開日: 2019-05-22)
主引用文献
Nikolova, E.N.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E.
A conformational switch at the zinc finger protein Kaiso directs recognitions of specific and methylated DNA
To Be Published,
実験手法
X-RAY DIFFRACTION (2.319 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.219200 7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード