6DF2
Improved anti-phosphotyrosine antibody 4G10-S5-4D5 Fab complexed with phosphotyrosine peptide
Summary for 6DF2
| Entry DOI | 10.2210/pdb6df2/pdb |
| Descriptor | Anti-phosphotyrosine antibody c310-4D5 heavy chain, Anti-phosphotyrosine antibody c310-4D5 light chain, LEU-PTR-LEU, ... (4 entities in total) |
| Functional Keywords | antibody, recombination, immune system |
| Biological source | synthetic construct More |
| Total number of polymer chains | 6 |
| Total formula weight | 111292.31 |
| Authors | Mou, K.,Leung, K.,Wells, J.A. (deposition date: 2018-05-13, release date: 2018-11-28, Last modification date: 2023-11-15) |
| Primary citation | Mou, Y.,Zhou, X.X.,Leung, K.,Martinko, A.J.,Yu, J.Y.,Chen, W.,Wells, J.A. Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140:16615-16624, 2018 Cited by PubMed: 30398859DOI: 10.1021/jacs.8b08402 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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