6DEB
Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni
Summary for 6DEB
Entry DOI | 10.2210/pdb6deb/pdb |
Descriptor | Bifunctional protein FolD, GUANINE, POTASSIUM ION, ... (9 entities in total) |
Functional Keywords | mthfdc, alpha-beta-fold, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
Total number of polymer chains | 2 |
Total formula weight | 63255.77 |
Authors | Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Grimshaw, S.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-05-11, release date: 2018-05-23, Last modification date: 2023-10-11) |
Primary citation | Kim, Y.,Makowska-Grzyska, M.,Maltseva, N.,Grimshaw, S.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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