6DDM

Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody

Summary for 6DDM

Entry DOI	10.2210/pdb6ddm/pdb
Descriptor	Anti-MICA Fab fragment light chain clone 1D5, MHC class I polypeptide-related sequence A, Anti-MICA Fab fragment heavy chain clone 1D5, ... (4 entities in total)
Functional Keywords	fab fragment-antigen complex, immunoglobulin domain, immune system
Biological source	Mus musculus More
Total number of polymer chains	3
Total formula weight	57239.75
Authors	Matsumoto, M.L. (deposition date: 2018-05-10, release date: 2018-10-24, Last modification date: 2023-10-11)
Primary citation	Lombana, T.N.,Matsumoto, M.L.,Berkley, A.M.,Toy, E.,Cook, R.,Gan, Y.,Du, C.,Schnier, P.,Sandoval, W.,Ye, Z.,Schartner, J.M.,Kim, J.,Spiess, C. High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11:75-93, 2019 Cited by PubMed: 30307368 DOI: 10.1080/19420862.2018.1532767 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation