6DDG
Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6
Summary for 6DDG
Entry DOI | 10.2210/pdb6ddg/pdb |
Related | 6DDD |
EMDB information | 7867 7870 |
Descriptor | 50S ribosomal protein L19, 50S ribosomal protein L28, 50S ribosomal protein L29, ... (28 entities in total) |
Functional Keywords | antibiotic complex, linezolid, oxazolidinone, 50s, ribosome, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Staphylococcus aureus More |
Total number of polymer chains | 27 |
Total formula weight | 1306299.35 |
Authors | Belousoff, M.J.,Venugopal, H.,Bamert, R.S.,Lithgow, T. (deposition date: 2018-05-10, release date: 2019-03-20, Last modification date: 2019-12-18) |
Primary citation | Belousoff, M.J.,Venugopal, H.,Wright, A.,Seoner, S.,Stuart, I.,Stubenrauch, C.,Bamert, R.S.,Lupton, D.W.,Lithgow, T. cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria. ChemMedChem, 14:527-531, 2019 Cited by PubMed: 30667174DOI: 10.1002/cmdc.201900042 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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