6DDA

Nurr1 Covalently Modified by a Dopamine Metabolite

Summary for 6DDA

Entry DOI	10.2210/pdb6dda/pdb
Descriptor	Nuclear receptor subfamily 4 group A member 2, POTASSIUM ION, 5-hydroxy-1,2-dihydro-6H-indol-6-one, ... (5 entities in total)
Functional Keywords	nurr1, dopamine, cysteine adduct, dihydroxyindole, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	93240.25
Authors	Bruning, J.M.,Wang, Y.,Otrabella, F.,Boxue, T.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M. (deposition date: 2018-05-09, release date: 2019-03-20, Last modification date: 2019-11-06)
Primary citation	Bruning, J.M.,Wang, Y.,Oltrabella, F.,Tian, B.,Kholodar, S.A.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M. Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol, 26:674-685.e6, 2019 Cited by PubMed: 30853418 DOI: 10.1016/j.chembiol.2019.02.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation