6DDA

Nurr1 Covalently Modified by a Dopamine Metabolite

6DDA の概要

• エントリーDOI: 10.2210/pdb6dda/pdb
• 分子名称: Nuclear receptor subfamily 4 group A member 2, POTASSIUM ION, 5-hydroxy-1,2-dihydro-6H-indol-6-one, ... (5 entities in total)
• 機能のキーワード: nurr1, dopamine, cysteine adduct, dihydroxyindole, transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 93240.25

構造登録者

Bruning, J.M.,Wang, Y.,Otrabella, F.,Boxue, T.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M. (登録日: 2018-05-09, 公開日: 2019-03-20, 最終更新日: 2019-11-06)

• 主引用文献: Bruning, J.M.,Wang, Y.,Oltrabella, F.,Tian, B.,Kholodar, S.A.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M.; Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite.; Cell Chem Biol, 26:674-685.e6, 2019; PubMed: 30853418; DOI: 10.1016/j.chembiol.2019.02.002

実験手法

X-RAY DIFFRACTION (3.2 Å)