6DD4

Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor

Summary for 6DD4

• Entry DOI: 10.2210/pdb6dd4/pdb
• Descriptor: Serine/threonine-protein kinase VRK1, CHLORIDE ION, ACETATE ION, ... (7 entities in total)
• Functional Keywords: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 166792.83

Authors

dos Reis, C.V.,Santiago, A.S.,de Souza, G.P.,Counago, R.M.,Azevedo, A.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (deposition date: 2018-05-09, release date: 2018-05-23, Last modification date: 2023-10-11)

• Primary citation: dos Reis, C.V.,Santiago, A.S.,de Souza, G.P.,Counago, R.M.,Azevedo, H.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC); Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)